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lower motor neuron
(redirected from Lower motor neurones)

   Also found in: Medical, Wikipedia 0.01 sec.
lower motor neuron [′lō·ər ′mōd·ər ‚nü‚rän]
(neuroscience)
An efferent neuron which has its body located in the anterior gray column of the spinal cord or in the brainstem nuclei, and its axon passing by way of a peripheral nerve to skeletal muscle. Also known as final common pathway.


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Motor neurone disease is a progressive neuro-degenerative disease that attacks the upper and lower motor neurones.
Progressive Bulbar Palsy (PBP) affects about 25 percent of sufferers and also involves both the upper and lower motor neurones but is characterised by dysarthria and dysphagia, and predominantly affects older women.
Amyotrophic Lateral Sclerosis ALS is the most common motor neurone disease resulting from progressive degeneration of both upper and lower motor neurones which lead to severe muscle weakness and wasting, followed by paralysis and death, generally caused by respiratory failure.
 
 
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