Corpus Luteum

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corpus luteum

[′kȯr·pəs ′lüd·ē·əm]
The yellow endocrine body formed in the ovary at the site of a ruptured Graafian follicle.

Corpus Luteum


in mammals and man, an endocrine gland that develops in the ovary at the site of the graafian follicle after rupture of the follicle wall and discharge of the ovum (ovulation); it consists of altered follicular (so-called lutein) cells. If pregnancy does not follow ovulation, the corpus luteum degenerates within one or two weeks (periodic, or menstrual, corpus luteum); if, however, the ovum is fertilized and pregnancy begins, the corpus luteum grows very rapidly (corpus luteum of pregnancy) and is retained throughout the greater part of pregnancy, secreting the hormone progesterone, which is necessary for the maintenance and development of the pregnancy.

The term “corpus luteum” is sometimes applied to the aggregate of follicular cells formed in the ovary at the site of discharge of the mature ovum in some invertebrates (insects) and in the majority of vertebrates (amphibians, reptiles, and birds).

References in periodicals archive ?
Luteal cells were round, with a large, central nucleus and were present inside the capsule of the CL.
After ovulation takes place, for a couple of days the former follicle--now the corpus luteum--fills up with these luteal cells, which make progesterone.
In vitro studies in luteal cells have shown that nicotine causes luteal insufficiency by inhibiting progesterone release (3).
Endometrial OXTR induced in the latter stages of the estrous cycle of ewes and cows, and a positive feedback loop between uterine PGF and OXT secretion by luteal cells induce pulsatile PGF secretion by increasing phospholipase C (PLC) activity leading to the production of inositol trisphosphate (IP3) and diacylglycerol (DAG).