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MHC

   Also found in: Dictionary/thesaurus, Medical, Legal, Acronyms, Wikipedia 0.04 sec.
MHC


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Working in collaboration with former postdoctoral assistant David Bos, who is presently a continuing lecturer at Purdue, DeWoody set out to see how much MHC genes affected mate choice in wild animals.
However, a substantial increase in MHC 2X isoform was observed with GH administration alone, and this may be regarded as a change into a more youthful MHC composition, possibly induced by the rejuvenating of systemic IGF-I levels.
The methods depend upon inhibiting invariant chain proteolysis by cathepsin S from class II MHC/invariant chain complexes, thereby reducing the competency of class II MHC molecules for binding antigenic peptides, reducing presentation of antigenic peptides by class II MHC molecules, and suppressing immune responses.
 
 
 
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