matrix metalloproteinase

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matrix metalloproteinase

[¦mā·triks mə‚tal·ō′prō·tē·ə‚nās]
(biochemistry)
Any member of a family of at least 19 structurally related zinc-dependent neutral endopeptidases collectively capable of degrading essentially all components of extracellular matrix.
References in periodicals archive ?
SAFRAN Electronics & Defense is a strategic partner of MBDA for a number of programs, including the MMP missile system where they are responsible for critical optronics elements namely: dismounted firing posts, sensors, commands, and missile seekers.
Studies on mutual relationships between extracellular matrix components, activity of metalloproteinases and content of tissue inhibitors in renal tumours usually demonstrate the increase in MMP activity and reduction in TIMP content in the course of neoplastic process.
In light of the above considerations, we set out the present study with the aim to evaluate the contribution of MMPs, namely, active MMP-9 and MMP-2, and the cytokines/chemokines IL-17, IL-18, IL-23, and MCP-3 to the pathogenesis of MS.
Treatment with MMP inhibitors blocks cell death in transient cerebral ischemic stroke [30, 35].
According to the company, Ingenico joins a roster of over 100 MMP licensees from a variety of industries, including electronics companies such as Hewlett-Packard, Sony, Nokia, General Electric, ASUStek, Amazon, Philips, Bosch, Cannon, Citizen, Sanyo, RIM, Brocade, Cummings, Emerson, Panasonic, Oracle, Roche, Caterpillar, Audiovox, Teac, Toshiba, Daewoo, Olympus, Stryker, Lego, Kenwood, Sharp, Fujitsu and Lexmark.
The effect of TNF-alpha increasing MMP levels in IBD patients with active disease might be the reason for the high MMP-3 levels in IBD group.
As evidence of effectiveness of MMPs inhibition, MMP9 activity was inhibited by 20 mg/kg SalA treatment (p < 0.
Por otro lado, se encuentran las MMP asociadas a membrana o MT-MMP que tienen una funcion importante en la activacion de progelatinasas como resultado de la degradacion de gran cantidad de componentes de la MEC.
2010) found higher expression of different types of MMP and TIMP in human prostates with carcinoma than in glands with benign changes, concluding that such enzymes have an important role in the molecular biology of prostatic carcinomas.
The MMP Portfolio includes US patents as well as their European and Japanese counterparts, which cover techniques that enable higher performance and lower cost designs essential to consumer and commercial digital systems ranging from PCs, cell phones and portable music players to communications infrastructure, medical equipment and automobiles.