Mona

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Related to MMP2: MMP9, TIMP1, TIMP3

Mona,

Roman name for the island of AngleseyAnglesey
or Anglesea
, island and county (1985 est. pop. 68,800), 278 sq mi (719 sq km), NW Wales. Beaumaris is the chief town. It is a region of low, rolling hills. The principal industries are agriculture and stock raising.
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, Wales. It was also sometimes used to designate the Isle of ManMan, Isle of,
island and dependency of the British crown (2005 est. pop. 75,000), 227 sq mi (588 sq km), off Great Britain, in the Irish Sea. The coast is rocky with precipitous cliffs; the Calf of Man is a detached rocky islet off the southwest coast.
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Mona,

island, Puerto Rico: see under Mona PassageMona Passage
, strait, c.80 mi (130 km) wide, between Puerto Rico and the Dominican Republic. Connecting the N Atlantic Ocean with the Caribbean Sea, it is a favored shipping lane, but its waters are treacherous for small craft.
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References in periodicals archive ?
To investigate whether E2, BPA, NP, and GEN could affect the migration of BG-1 ovarian cancer cells, the alterations in protein expression of MMP2 and cathepsin D which are used as cell migration and metastatic markers (Lee and Choi 2013) for being actively expressed during cancer metastasis process were measured after 48 h of the treatment of each reagent to BG-1 cells.
It also has been shown that exposure of PSCs to ethanol and acetaldehyde in vitro increases the secretion of MMP2, which may contribute to pancreatic fibrosis, as described above.
This research investigated the mechanisms by which an anti TGF-[beta] antibody to all the TGF-[beta] isoforms (1-3), and an anti TGF-[beta]1 antibody regulate the MMP-1 and MMP2 genes.
Matrix degradation- and endothelial cell migration-related factors were up-regulated, including: MMP2 (fold change, 4.
More recently, MMP2 has been shown to influence lymphangiogenesis through its interstitial collagenolytic activity (30).
In the present studies, we demonstrated that radiation (10 Gy) induced an immediate increase in the amounts and activation of MMP1 and MMP2 in the cell fraction and medium of bovine capillary endothelial cells followed by an incidence of apoptosis.
XL784 is a potent small molecule inhibitor of MMP2 and ADAM10, metalloprotease enzymes that may play a role in renal fibrosis and impairment.
Prolactin increased MMP2 secretion and in combination with estrogen increased it further after 48 and 72 hours of hormone treatmen t.
The enzyme activity of MMP-9 was suppressed by CV dose-dependently, while the activity of MMP2 was not affected by CV treatment.
At least 25 MMPs have been described, and MMP2, MMP3, and MMP9 seem to play the largest role in the development of HF.
TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents Is partially regulated by MMP2.
Other findings from the research teams included: * Development of a biomarker set including MMP2 and MMP3 levels, HLA genotype, and the DQB1 mRNA expression profile which predicted RA patients with higher disease activity; * A combination of clinical and genetic variables which might predict patients at risk for erosive disease; * A combination of clinical and genetic variables which might distinguish RA patients who have achieved remission; and * Patients in remission and those with active disease have 28 differentially expressed genes when they are HLA-DRB1 SE negative, a well-established genetic marker for RA.