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macropinocytosis |
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macropinocytosis [‚mak·rō‚pin·ə‚sī′tō·səs] (cell and molecular biology) A mechanism of endocytosis in which large droplets of fluid are trapped underneath extensions (ruffles) of the cell surface. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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There are at least four basic mechanisms, most of which can be demonstrated in lungs and involve specific receptor-ligand interactions: a) macropinocytosis, b) clathrin-mediated, actin-based endocytosis, c) caveolae-mediated endo- or transcytosis, and d) clathrin- and caveolae-independent endocytosis (Conner and Schmid 2003). nbsp;dysentery in humans, directs its own uptake into the colonic mucosa through membrane ruffling and macropinocytosis in a manner similar to Salmonella uptake (43,44). 2004) reviewed a number of different endocytic pathways for internalization of a variety of substances, including phagocytosis, macropinocytosis, clathrin-mediated endocytosis, and caveolae-mediated endocytosis. |
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