malacoplakia

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malacoplakia

[‚mal·ə·kə′plā·kē·ə]
(medicine)
The accumulation of modified histiocytes (malacoplakia cells) to produce soft, pale, elevated plaques, usually in the urinary bladder of middle-aged women.
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Rhodococcus equi pneumonia and pulmonary malakoplakia in acquired immunodeficiency syndrome: pathologic features.
Although no characteristic Michaelis-Gutmann bodies were seen, the staining characteristics of the intracellular coccobacilli were compatible with Rhodococcus equi, a pathogen associated with malakoplakia.
Malakoplakia involving the abdominal wall, urinary bladder, vagina, and vulva: Case report and discussion of malakoplakia-associated bacteria.
They may manifest as abnormal intestinal soft tissue reactive changes (eg, inflammatory fibroid polyp [IFP]), exuberant prolapse-induced changes (eg, colitis cystica profunda), unusual-appearing cellular changes (eg, malakoplakia, bizarre stromal cells [BSC], or benign signet ring cells), and morphologic findings made unusual by their location (heterotopias).
Malakoplakia may be a pitfall because of the epithelioid histiocytes in the lamina propria infiltrate, the cells of which can also be confused with carcinoma.
Hamodat, contributing information about a case report of malakoplakia of the neck, which was mentioned in the article.
If we rule out the very unusual heterotopic spleen in the pancreatic tail, which can simulate an endocrine tumor, 5 and rare cases of infectious conditions such as malakoplakia, 6 mycobacteria, (7) and fungal infections, (8) most of the "solid" cases fall into the category of inflammatory and fibrosis conditions correlated in various ways with chronic pancreatitis (CP).
Nonneoplastic Conditions in Nephrectomy Specimens Medical renal diseases in nephrectomy specimens removed for renal neoplasms Obstructive nephropathy/reflux nephropathy Nephrectomy specimens from patients with end-stage renal disease Renal arterial stenosis Renal inflammatory/infectious conditions Xanthogranulomatous pyelonephritis Malakoplakia Abscess Tuberculosis Cystic renal diseases Polycystic kidney disease, autosomal dominant Polycystic kidney disease, autosomal recessive Dysplastic kidney Traumatic rupture Table 2.
In addition to the urinary tract, malakoplakia has been reported in other organs, including the gastrointestinal tract, central nervous system, female genital tract, and the tongue.
28) Malakoplakia of the testis can also look similar to LCT grossly as it may form a single, homogeneous, yellow or brown mass.
Malakoplakia, a Greek term meaning soft (malako) plaque (plakia), is an unusual inflammatory process.
Michaelis-Gutmann bodies would be diagnostic of malakoplakia.