Neurofibroma

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Related to Malignant Schwannoma: malignant meningioma

neurofibroma

[¦nu̇r·ō·fī′brō·mə]
(medicine)
A tumor characterized by the diffuse proliferation of peripheral nerve elements. Also known as endoneural fibroma; myxofibroma of nerve sheath; neurofibromyxoma; perineural fibroblastoma; perineural fibroma.

Neurofibroma

 

a benign tumor that originates in membranes of peripheral nerves and is localized in any part of the body along the path of a nerve trunk. Neurofibromas most often affect the sciatic and intercostal nerves. The multiple occurrence of neurofibromas is called neurofibromatosis.

References in periodicals archive ?
As shown in Table 2, the incidence of malignant schwannomas of the peripheral nerves occurred with a positive trend (p [less than or equal to]0.
The overall incidence of malignant schwannomas was 0.
05); and d) an increased incidence of malignant schwannomas of the peripheral nerves with a positive trend (p [less than or equal to] 0.
Malignant schwannoma associated with von Recklinghausen's neurofibromatosis.
Malignant schwannoma is a highly aggressive tumor that carries a poor prognosis.
In this article, we describe the clinical history of a young man affected by neurofibromatosis type 1 whose neurofibroma of the parapharyngeal space transformed into a malignant schwannoma.
Frozen-section examination of the tumor specimen confirmed the suspicion that it represented a neurofibroma that had transformed into a malignant schwannoma.
On macroscopic examination, the cut surface was grayish-white and exhibited focal myxoid areas, The lesion was diagnosed as a malignant schwannoma.
A final diagnosis of malignant schwannoma (neurofibrosarcoma) was arrived at in both cases.
The researchers "also observed an insignificant increase in incidence of malignant schwannomas of the peripheral nerves in males, as well as hyperplasia of the olfactory epithelium in males and females.
Leiomyosarcomas can be confused histologically with other spindle cell sarcomas, especially fibrosarcomas, malignant schwannomas, and malignant fibrous histiocytomas.

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