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(1) In the kidneys of man and almost all vertebrate animals (except some fish), tufts of arterial capillaries (glomeruli) surrounded by Bowman’s capsules. Filtration of fluid from the blood into the uriniferous tubules takes place in the Malpighian corpuscles. The total number of Malpighian corpuscles in man is up to 4 million.
(2) In the reticular tissue of the spleen in vertebrate animals and in man, the lymph nodules in which the formation of lymphocytes occurs. The Malpighian corpuscles are distributed around the small branches of the splenic artery.