QFT is the first major advance in TB diagnosis since the introduction of the Mantoux
or tuberculin skin test (TST) over 100 years ago.
skin test involves injecting a small amount of purified sterile protein just under the skin in the forearm.
3) A positive Mantoux
test is also used to confirm the diagnosis.
Screening of potential contacts is done by using the Mantoux
tuberculin skin test (TST); induration of [greater than or equal to] 5 mm is considered positive for this test (9).
A study of more than 1 500 children <5 years old who underwent tuberculin skin testing with both Mantoux
and Tine tests showed that a significantly higher proportion tested positive on Tine testing (32.
Delayed hypersensitivity as detected by Mantoux
testing is generally accepted as a reflection of the level of cell-mediated immunoactivity--the less hypersensitivity reaction that occurs, the lower the level of immunoactivity is, and vice versa.
Children with a positive mantoux
test are referred to the Children's TB clinic at Starship Hospital.
Titled "Tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control", the NICE recommendations state that screening for latent TB infection - which has no symptoms and is not infectious but has the potential to develop into TB disease at any time - will include administering the unlicensed Mantoux
tuberculin skin test in the first instance and, if the results are positive, conducting a further blood test (also known as an interferon-gamma immunological test) to confirm the accuracy of the skin test.
Seven out of 10 nurses have said using the Mantoux
skin test for detecting latent TB infection is a step backwards and more than a third believe it is a major set back in the fight against TB, according to a new survey.
TB by Mantoux
tuberculin skin test (TST), and health authorities decided to test all school children and staff.
test was positive and antituberculous treatment was administered.
The school also will require proof of immunizations, proof that a Mantoux
tuberculosis test was taken, and proof of residence.