Lyon hypothesis

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Lyon hypothesis

[′lī·ən hī‚päth·ə·səs]
(genetics)
The concept that mammalian females are X-chromosome mosaics as a result of the random inactivation of one X chromosome in some embryonic cells and their descendant and of the other X chromosome in the rest.
References in periodicals archive ?
Building on those data as well as her own work on mice with mottled coats, Mary F.
WHAT: Black tie event to award the 2004 March of Dimes Prize in Developmental Biology to Mary F.
The corrected release reads: WHAT: Black tie event to award the 2004 March of Dimes Prize in Developmental Biology to Mary F.