mastocytosis

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Related to Mast cell disease: systemic mast cell disease

mastocytosis

[¦mas·tə‚sī′tō·səs]
(medicine)
Excessive mast cell proliferation. Also known as mast-cell disease.
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Mast cell disease is uncommon in birds, and, to our knowledge, this is the first reported case of a cutaneous mast cell tumor and mastocytosis in a psittacine bird.
14) Mast cell disease has been documented in numerous small domestic mammals and occasional reptilian species, including dogs, (15-20) cats, (15,16,21,22) ferrets, (23-26) hedgehogs, (27) a snake, (28) and a chelonian.
Tryptase levels stay consistently elevated in those with under-lying mast cell disease (17).
Clinical, genetic, and therapeutic insights into systemic mast cell disease.
Key Words: hypotension, mast cell disease, mastocytosis, urticaria pigmentosa
Immunohistochemical characterization of mast cell disease in paraffin sections using tryptase, CD68, myeloperoxidase, lysozyme, and CD20 antibodies.
The c-Kit proto-oncogene is a receptor protein tyrosine kinase associated with highly malignant human cancers, including acute myelogenous leukemia (AML), mast cell disease and gastrointestinal stromal tumors (GISTs).