megaloblastic anemia

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megaloblastic anemia

[¦meg·ə·lō¦blas·tik ə′nē·m̄e·ə]
(medicine)
Anemia characterized by the occurrence of megaloblasts in the bone marrow and blood.
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Megaloblastosis (a known side effect of HU) has been postulated to play a role, too, as the enlarged red blood cells circulate less easily in small blood vessels (3),(10).
Red cell indices in megaloblastosis and iron deficiency.
Megaloblastosis is characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow [Figure 4] and also by hypersegmented neutrophils having five or more nuclear lobes in more than 5% of cells in the peripheral smears