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Methemoglobinemia
(redirected from Methaemoglobinaemia)

    Also found in: Medical, Wikipedia 0.01 sec.
methemoglobinemia [¦met‚hē·mə·glō·bə′nē·mē·ə]
(medicine)
The presence of methemoglobin in the blood.
Methemoglobinemia 

the appearance of methemoglobin in the blood as a result of the toxic effect of various chemical substances (nitrates and nitrites, aniline, pyridine) that are capable of converting hemoglobin to methemoglobin (MtHb) upon entering the body through the skin, digestive tract, or lungs. With considerable methemoglobinemia, oxygen starvation, or hypoxia, may result. Methemoglobin may be excreted with the urine (methemoglobinuria); this is sometimes damaging to the kidneys. Methemoglobinemia is treated with antidotes (methylene blue, ascorbic acid) and oxygen therapy.
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There have been reports of prilocaine causing methaemoglobinaemia.
Local anaesthetics: characteristics, uses and toxicities: an ... by Du Plessis, Rene / CME: Your SA Journal of CPD
Experts said the pair were "very lucky" to have survived after contracting methaemoglobinaemia, which is linked to bingeing on cocaine.
Update: Cocaine alert as two fight for life by Sunday Mail (Glasgow, Scotland)
The significance of methaemoglobinaemia induced by prilocaine (Citanest).
Anesthetic management of a patient with methemoglobinemia by Norman, Peter H. / Southern Medical Journal
 
 
 
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