The Kandha tribe of Orissa, India uses the dried seeds of the plant to cure impotency, spermatorrhea, leucorrhea, metrorrhagia
, sexual neurasthenia, and sexually transmitted diseases (Behera, S.
Severe adverse reactions reported in the clinical trial of juvenile idiopathic arthritis (JIA) included neutropenia, streptococcal pharyngitis, increased aminotransferases, herpes zoster, myositis, metrorrhagia
American College of Radiology Guidelines for indications for ultrasound of the female pelvis (1) Pelvic pain Dysmenorrhea Menorrhagia Metrorrhagia
Menometrorrhagia Follow-up of previously detected abnormality (eg, hemorrhagic cyst) Evaluation and/or monitoring of infertile patients Delayed menses or precocious puberty Postmenopausal bleeding Abnormal pelvic examination Further characterization of abnormality noted on another imaging study Evaluation of congenital anomalies Excessive bleeding Pain or fever after pelvic surgery or delivery Localization of intrauterine contraceptive device Screening for malignancy in patients with increased risk Table 2.
Technically defined as blood loss >80 cc or bleeding that lasts >7 days * Polymenorrhea -- Increased frequency of bleeding (interval <21 days) * Oligomenorrhea -- Decrease in frequency of bleeding (interval >35 days) * Metrorrhagia
-- Irregular interval of bleeding, typically between cycles * Menometrorrhagia -- prolonged or excessive bleeding both at time of menstruation and other irregular intervals * Intermenstrual bleeding -- bleeding that occurs between regular menstrual cycles * Dysfunctional uterine bleeding -- excessive endometrial bleeding that is unrelated to anatomic or systemic disease; classically anovulatory bleeding, as this is the primary cause Table 2.
= Irregular and frequent (occurring at least twice within 28-32-day cycle) uterine bleeding.
Adverse events that were reported more than once were headaches and metrorrhagia
, events that are listed in the label of Ortho Tri-Cyclen, and convulsions, an adverse event that is not in the label.
The hemorrhagic manifestations in 297 of these patients were metrorrhagia