Lesch-Nyhan syndrome

(redirected from Michael Lesch)
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Lesch-Nyhan syndrome

[′lesh ′nī‚han ‚sin‚drōm]
(medicine)
A hereditary disease of male children, transmitted as an X-linked recessive, characterized by hyperuricemia, deficiency of hypoxanthine-guanine phosphoribosyl transferase, mental retardation, spastic cerebral palsy, choreathetosis, and self-mutilating biting.
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Lesch-Nyhan disease was first described in 1964, by two physicians named Michael Lesch and William Nyhan.