Immunosuppression after traumatic or ischaemic CNS damage: it is neuroprotective and illuminates the role of microglial cells
Caffeine suppresses lipopolysaccharide-stimulated BV2 microglial cells
by suppressing Akt-mediated NF-[kappa]B activation and ERK phosphorylation.
Cell culture and measurements of NO and intracellular ROS production by microglial cells
The data reported at AAIC demonstrates the potential of new target structures -- such as cannabinoid type 2, P2X7 and COX2 receptors -- to more accurately reflect various stages or types of the microglial cells
, telling us if they're being destructive or protective," said Jacobs.
, the nervous system's defenders, are unable to eliminate this substance, which forms deposits called senile plaques.
Reactions of astrocytes and microglial cells
around hematogenous metastases of the human brain.
are the brain's first and primary immune defense.
The surrounding tissue was gliotic and contained a mixed inflammatory infiltrate including perivascular lymphocytes and plasma cells as well as microglial cells
with loose microglial nodule formation (Figure 3).
Pro-inflammatory cytokines can penetrate the blood-brain barrier and affect those microglial cells
located in specific areas of the brain involved in mood regulation and reward process.
A biopsy specimen of the pontine lesion in December 2010 showed a reactive, T-cell-predominant, CD3-positive, lymphocytic infiltrate with scattered macrophages and microglial cells
with few plasma cells (Figures 2A, B and 3A, B).
Within the cerebellum and piriform plexus, diffuse mild vacuolation of the grey and white matter was present along with mildly increased numbers of microglial cells
Its innovative line of research is to control the activity of microglial cells
involved in a wide range of diseases related to brain inflamation or acute cerebral damage.