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Microsome
(redirected from Microsomes)

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microsome [′mī·krə‚sōm]
(cell and molecular biology)
A fragment of the endoplasmic reticulum.
A minute granule of protoplasm.
Microsome 

a fragment in the endoplasmic network (bubbles about 1,000 angstroms diameter), formed when cells are destroyed during the homogenization of animal and plant tissues. The microsome fraction of the homogenate is isolated by differential centrifugation. There are two types of microsomes: smooth-surfaced and rough-surfaced (as a result of the distribution of ribosomes on the latter). Before the technique of separating cellular homogenates was perfected, the microsome fraction also included mitochondria.
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Inhibition of free radical-induced peroxidation of rat liver microsomes by resveratrol and its analogues.
Resveratrol protects auditory hair cells from gentamicin toxicity by Bonabi, Sharouz; Caelers, Antje; Monge, Arianne; Huber, Alex; Bodmer, Daniel / Ear, Nose and Throat Journal
Previous workers had separated cell parts into four fractions - nuclei, mitochondria, microsomes and soluble components.
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Sellers and Tyndale (6) have found that menthol inhibits the metabolism of nicotine and cotinine using human liver microsomes as well as by cDNA expressed CYP2A6.
Mentholated cigarette smoking induced alterations in left and right ... by Ciftci, Ozgur; Caliskan, Mustafa; Gullu, Hakan; Yildirir, Aylin; Muderrisoglu, Haldun / The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi)
 
 
 
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