12,13 Although this resistance appears to be multifactorial; defects in tubulin and microtubule-associated proteins
(MAPs), dysregulated cell cycle and apoptotic signaling pathways are among the factors thought to be responsible for taxane resistance.
2013) Spatial organization of xylem cell walls by ROP GTPases and microtubule-associated proteins
as targets in cancer chemotherapy.
PAR-1 and the microtubule-associated proteins
CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles.
Abnormal expression of two microtubule-associated proteins
(MAP2 and MAP5) in specific subfields of the hippocampal formation in schizophrenia, Proc.
Other neuronal marker proteins that have been identified in central neurocytoma include neurofilament protein, neuron-associated class III [beta]-tubulin, and microtubule-associated proteins
MAP2 and tau.
In addition, phosphorylation of microtubule-associated proteins
(MAPS) and actin-associated proteins may induce alterations of polymerization of MTs and distribution of MFs (30,31).
MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins
and trigger microtubule disruption.
This newly issued patent describes a method of determining the presence of neural injury through the measurement of proteolytic breakdown products of microtubule-associated proteins
JNK exerts its effects on the cytoskeleton by phosphorylating numerous microtubule-associated proteins
(MAPs) such as MAP2, MAP1B, tau and the stathmin family microtubule-destabilizing protein SCG10.
On the molecular level, plectin binds to a variety of cytoskeletal proteins, including cytoplasmic and nuclear IF subunit proteins (vimentin, GFAP, cytokeratins, neuro-filament proteins, lamin B), subplasma membrane proteins (fodrin and [Alpha]-spectrin), and high molecular weight microtubule-associated proteins
MAP1 and MAP2 (Herrmann and Wiche, 1987; Foisner et al.
Such a bundling mechanism can be applied to a class of cationic actin-bundling proteins, including smooth muscle calponin and the microtubule-associated proteins
tau and Map2c.