We investigated the impact of microtubule
destabilization and dechanneling therapy on a suppression of refractory electrical storm (ES) in a 63-year-old male patient with ischaemic heart failure with reduced left ventricular ejection fraction (HFrEF), who had a history of previous coronary artery bypass grafting and implantable cardioverter-defibrillator (ICD).
Eggs stained for microtubules
or for centrosomes were labeled with the goat antimouse IgG (H + L) secondary antibody pretagged with Alexa Fluor 488 conjugate diluted to 5 [micro]L/mL by 1 % BSA/PBS (containing 0.
For their research, the scientists extracted microtubules
from the brain tissue of cows, and mixed them kinesin - a protein that attaches to the microtubules
- and adenosine triphosphate (ATP) - often called the "molecular unit of currency" of intracellular energy transfer.
and Chromosomes in Different Phase
it was recently revealed that curcumin interacts with a specific binding site on microtubules
and suppresses their dynamic instability in many types of cancer cells (Banerjee et al.
However, more recent work has indicated that astral microtubules
are not required for echinoderm cytokinesis, suggesting that central spindle signaling is taking place, perhaps in a microtubule
-independent manner (von Dassow et al.
In the next laboratory step, these travelling protein microtubules
, microns in length, encounter relatively large polymer spheres, tens of microns in diameter, inserted by the researchers.
Data were analyzed using one-way ANOVA with Scheffe post-hoc test, and Welch's t-test for examining the effect of cAMP on the number of fibers of doublet microtubules
and for detecting the difference in the three-dimensionality between asymmetrical and symmetrical flagellar movement of the hyperactivated spermatozoa, using SPSS 11.
The connection between these two cellular components--microtubules
and cell-cell junctions--occurs via the interaction between the CLASP2 and pi20 catenin proteins, linked to microtubules
and cell junctions respectively.
However, this study found that microtubules
could additionally develop from the chromosomes themselves, or at arbitrary sites throughout the main body of the cell, if the centrosomes were missing.
But certain fundamental data remain missing, particularly concerning the relationship between the amount of microtubules
and the size and shape of spindles
The four plastids serve as plastid-MTOCs and cones of microtubules
emanating from them interact to further define cytokinetic planes and initiate a quadripolar spindle.