mifepristone


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mifepristone

an antiprogestogenic steroid, used in the medical termination of pregnancy. Formula: C29H35NO2
References in periodicals archive ?
But in English that means researchers from Gynuity Health Projects were studying what the results might be if women could purchase mifepristone and misoprostol by mail order to use at home.
Mifepristone 200 mg was found to be as effective as 600 mg in multicentre trials by WHO.
Utah's law, meanwhile, requires that physicians explain "the options and consequences of aborting a medication-induced abortion" and inform women that mifepristone alone is not always effective in ending a pregnancy.
Under FDA restrictions, the manufacturer wasn't allowed to supply mifepristone to pharmacies; instead, it had to ship it only to physicians who registered with the company.
Roussel Uclaf accomplished a comprehensive study in the mid 1980s announcing the safety of the molecule and allowing mifepristone to be used in humans5.
First approved in 2000, mifepristone, when taken with another drug called misoprostol, is used to terminate early pregnancies.
In China, oral administration of mifepristone and misoprostol for the termination of pregnancy in weeks 10-16 and intra-amniotic injection of ethacridine lactate (EL; Rivanol [sup][R] ) for the termination of gestation after the 16 [sup]th week are the standard procedures in clinical practice.
Several studies have compared the efficacy of combination therapy of misoprostol and mifepristone with misoprostol alone in early pregnancy termination.
In a constitutional challenge to Ohio's ban on off-label use of mifepristone, a Sixth Circuit panel affirmed the state's motion for summary judgment on Planned Parenthood's claims that the law was unconstitutionally vague, violated patients' right to bodily integrity, and that it posed an undue burden to women seeking an abortion in the state of Ohio.
Many years of use in Europe had proven its safety and efficacy, yet social conservatives in the political realm cited spurious safety concerns about mifepristone in efforts to keep the drug out of the US market.
METHODS: At 10 facilities in Bangladesh, 651 consenting women who were seeking menstrual regulation services and who were 63 days or less past their last menstrual period received 200 mg of mifepristone followed 24 hours later by 800 mcg of buccal misoprostol, administered either at home or in the clinic.