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missense mutation
(redirected from Missense mutations)

   Also found in: Medical, Wikipedia 0.01 sec.
missense mutation [′mis·əns myü′tā·shən]
(cell and molecular biology)
A mutation that converts a codon coding for one amino acid to a codon coding for another amino acid.


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Rachel Karchin, an assistant professor of biomedical engineering, and doctoral student Hannah Carter have revealed that the new process focuses on missense mutations, meaning protein sequences that each possess a single tiny variation from the normal pattern.
Two novel missense mutations in the thyroid peroxidase gene, R665W and G771R, result in a localization defect and cause congenital hypothyroidism.
Seven of nine MDR W-Beijing strains carried missense mutations in two muT genes (mutT2 and mutT4), and two had a missense mutation in both mutT4 and ogt (Table 1 and 2).
 
 
 
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