Post hoc analyses presented at the 25th European College of Neuropsychopharmacology (ECNP) congress show asenapine achieves significant control of mixed episodes
in bipolar I disorder compared to placebo.
Of course, during a manic or mixed episode
, individuals may also have extreme reactions to events, but by definition their mood difficulties must persist for a sustained period.
Acute treatment of manic or mixed episodes
associated with Bipolar I Disorder as monotherapy and as an adjunct to lithium or valproate for adults and pediatrics 10 to 17 years of age
Among other indications, aripiprazole is approved for the acute treatment of manic or mixed episodes
associated with bipolar I disorder as monotherapy in adults and pediatric patients aged 10-17 years, and as monotherapy for the maintenance treatment of bipolar I disorder in adults and adolescents aged 13-17 years.
Food and Drug Administration-approved agents for treatment of manic symptoms of bipolar mixed episodes
include most atypical antipsychotics (paliperidone [Invega], quetiapine [Seroquel], and clozapine excepted) and long-acting formulations of the anticonvulsants divalproex sodium (Depakote) and carbamazepine.
Results from three separate controlled trials in adults with manic or mixed episodes
of bipolar I disorder showed cariprazine (Vraylar) was associated with improved total scores on the Young Mania Rating Scale (YMRS), compared with placebo.
At this time, the best that we are able to conclude about the relative efficacy of the three new SGAs is that all are superior to placebo in the acute treatment of acute schizophrenia, and, in the case of Saphris, manic or mixed episodes
associated with bipolar I disorder.
treatment of schizophrenia and manic or mixed episodes
associated with bipolar
They also address the management of manic and mixed episodes
and depressive episodes, longer-term management, and rapid cycling.
Leading doctors practicing in the UAE threw light on mental illnesses prevailing in the country and discussed the effectiveness of Quetiapine Sustained Release, approved by the FDA (Food and Drug Administration) for the treatment of acute depressive, manic and mixed episodes
of bipolar disorder.
The Food and Drug Administration has approved the atypical antipsychotic aripiprazole (Ability) for the treatment of manic and mixed episodes
associated with bipolar I disorder in children and adolescents.
from Michigan City, Indiana: Geodon is FDA-approved to treat schizophrenia and bipolar disorder with acute manic or mixed episodes