Medications frequently prescribed include tricyclic anti-depressants, high-potency benzodiazepines, monoamine oxidase inhibitors
(MOAIs) and selective serotonin reuptake inhibitors (SSRIs).
Avoid use of Karbinal ER with monoamine oxidase inhibitors
(MAOIs) which prolong and intensify the anticholinergic (drying) effects of antihistamines.
Selective serotonin reuptake inhibitors are probably high on most physicians' list of possible treatments because unlike tricyclics they don't cause weight gain and other troubling effects such as cardiac arrhythmia, and, unlike monoamine oxidase inhibitors
, they aren't lethal in overdose.
The global depression drugs market is segmented based on the mechanism of action of the drugs used to treat depression, as mentioned below: - Tricyclic antidepressants - Serotonin-norepinephrine reuptake inhibitors - Selective serotonin reuptake inhibitors - Monoamine oxidase inhibitors
- Others Technavio's report, Global Depression Drugs Market 2015-2019, has been prepared based on an in-depth market analysis with inputs from industry experts.
Tricyclic antidepressants and monoamine oxidase inhibitors
are effective in treating bipolar depression but can produce dangerous side effects and carry the highest risk of any drugs for switching patients to mania.
Other treatment types include analogues of GABAs (gamma-aminobutyric acids), such as Remeron; monoamine oxidase inhibitors
(MAOIs) such as Parnate, Neurontin, Lyrica and Nardil.
Dexmethylphenidate HCl extended-release capsules are contraindicated in patients with marked anxiety, tension, and agitation, since the drug may aggravate these symptoms; patients known to be hypersensitive to methylphenidate or other components of the product; patients with glaucoma; patients with motor tics or with a family history or diagnosis of Tourette's syndrome; and during treatment with monoamine oxidase inhibitors
, and also within a minimum of 14 days following discontinuation of treatment with a monoamine oxidase inhibitor
(hypertensive crises may result).
Tramadol has a dual action, as a weak opioid and a serotonin and norepinephrine reuptake inhibitor, and may interact with antidepressants, especially the monoamine oxidase inhibitors
moclobemide and pirlindole, to induce a serotonin syndrome," Dr.
In fact, these same effects have been seen with serotonin and/or norepinephrine selective reuptake inhibitors, monoamine oxidase inhibitors
, tricyclic antidepressants, lithium, and electroconvulsive therapy (both single and multiple exposure).
Xenazine[R] is also contraindicated in patients with impaired hepatic function, and in patients taking monoamine oxidase inhibitors
Although the incidence and prevalence of sexual dysfunction vary depending on a number of factors, the general consensus is that 30-65% of patients experience sexual dysfunction while receiving selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and monoamine oxidase inhibitors
Numerous trials have been conducted showing the efficacy of this augmentation strategy when lithium is combined with tricyclic antidepressants, monoamine oxidase inhibitors
, or serotonin reuptake inhibitors (Can.