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Monocytes

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Monocytes 

a form of nongranular white blood cells (agranulocytes) that form in the bone marrow. They usually have a kidney-shaped nucleus and a weakly basophilic cytoplasm. In human blood, monocytes normally account for 4–8 percent of the leucocytes. Their diameter is 12–20 microns. Monocytes are capable of phagocytosis and, upon separating from the blood into the tissues, become macrophages.



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The team discovered that radiation kills monocytes, a type of white blood cell, in the arterial wall, which results in higher levels of monocyte chemo-attractant protein 1 (MCP-1) and leads to cardiovascular disease.
In the new study, scientists add to this list of duties, showing that the spleen stores monocytes in compartments close to mainstream blood vessels.
During its next stage, the study aims to expand recruitment to achieve a total of about 20,000 cases and about 20,000 controls, and, in subsets of participants, to enrich the resource by collection of monocytes, establishment of lymphoblastoid cell lines, and by resurveying participants.
 
 
 
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