Moore, Stanford

Moore, Stanford,

1913–82, American biochemist, b. Chicago, Ph.D. Univ. of Wisconsin, Madison, 1938. Moore joined the faculty at the Rockefeller Institute for Medical Research (now Rockefeller Univ.) in New York in 1939 and remained there until his death in 1982. He received the 1972 Nobel Prize in Chemistry with Christian AnfinsenAnfinsen, Christian Boehmer,
1916–95, American biochemist, b. Monessen, Pa., Ph.D. Harvard Medical School, 1943. He spent the early years of his career in brief research and fellowship positions at various medical institutions and agencies.
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 and William SteinStein, William Howard,
1911–80, American biochemist, b. New York City, Ph.D. Columbia, 1937. Stein was a professor at the Rockefeller Institute for Medical Research (now Rockefeller Univ.) from 1937 until he retired in 1971.
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 for their work on the enzyme ribonuclease, which catalyzes the hydrolysis of RNA into smaller components. Moore and Stein are credited with describing in detail the chemical structure of catalytically active sites on the enzyme and their relation to the enzyme's biological activity.

Moore, Stanford

 

Born Sept. 4, 1913, in Chicago. American biochemist. Member of the US National Academy of Sciences and of the American Academy of Arts and Sciences.

Moore graduated from Vanderbilt University in 1935. Beginning in 1939 he worked at the Rockefeller Institute for Medical Research (now Rockefeller University) in New York City, where he became a professor of biochemistry in 1952. From 1950 to 1951, Moore gave a series of lectures at the University of Brussels (Belgium); in 1951 he conducted research at Cambridge University (England). He studied the structure of a number of proteins, primarily the enzyme ribonuclease, and developed the chromatographic technique of chemical analysis. Moore worked with W. Stein on the development of automatic apparatus for the chromatographic separation and quantitative determination of amino acids. In 1972 he was awarded the Nobel Prize for Chemistry (with C. Anfinsen and W. Stein) for his pioneering work in the chemistry of enzymes.

Moore, Stanford

(1913–82) biochemist; born in Chicago. He was affiliated with Rockefeller Institute for most of the years from 1939 until his death. Using ion-exchange chromatography, he and William Stein analyzed the amino acids present in a variety of proteins; in 1960, they mapped out the complete amino acid sequence of ribonuclease. He shared the Nobel Prize in chemistry with William Stein for this work (1972).
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