Mucins


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Mucins

 

secretions from epithelial cells in the mucosa of respiratory, digestive, and urogenital tracts, as well as from the submaxillary and sublingual salivary glands. Mucins are mixtures of the carbohydrate-protein compounds known as glycoproteins and impart moisture and elasticity to the mucosa. Salivary mucins promote the moistening and adhesion of food particles for smooth passage through the esophagus. Covering the gastrointestinal mucosa, mucins provide protection from the action of proteolytic enzymes in gastric and intestinal juices. Mucins perform an overall protective function in the organism; for example, they inhibit the erythrocyte agglutination caused by the influenza virus.

References in periodicals archive ?
Low-grade/well-differentiated mucinous adenocarcinoma with PMP showed appendiceal rupture with mucin extravasation into the abdomen.
4) In addition, mucins regulate the differentiation, proliferation, and tumor suppression of tumor cells.
2) was characterized by a single layer of simple, uniform columnar cells of approximately 60-70 [micro]m in thickness, interspersed sporadically with large goblet cells containing neutral and acidic mucins.
Beta-casomorphin-7 regulates the secretion and expression of gastrointestinal mucins through a mu-opioid pathway.
Small intestinal mucins are secreted in proportion to the settling volume in water of dietary indigestible components in rats.
The fact that similar expression pattern of membrane-associated mucins occurs in cultivated oral mucosal epithelial sheets and in limbal epithelium may be one of the reasons for the efficient of ectopic transplantation of a cultivated oral mucosal epithelial sheet on the cornea of patients with ocular surface diseases (9,19).
The more purulent the sputum the less likely it is to contain mucin, and it has similar composition to pus.
With a simpler carbohydrate structure than that of other animal mucius, qniumucin could serve as a foundation for more-complex synthetic mucins tailored to specific applications, Ushida says.
The subsequent examination of the histopathologic materials revealed the extramucosal presence of numerous fungal hyphae in the mucin layer.
Babies probably make their own mucins as they develop.
The conjunctiva is largely responsible for the production of mucins within the eye, which play an essential role in maintaining a healthy tear film.