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Related to Myasthenia: Ocular myasthenia


Muscular weakness.



(asthenic bulbar paralysis, asthenic ophthalmoplegia, pseudobulbar paralysis, Erb-Goldflam disease), a neuromuscular disease characterized by the pathological, rapid fatigability of striated muscles.

The onset of myasthenia usually occurs between the ages of 20 and 40 years; women are more frequently affected, Autoimmune processes play a part in the development of the disease; antibodies have been discovered in muscle tissue and in the thymus gland. The muscles of the eyelids are often affected and there is ptosis, which varies in degree during the day; the masticatory muscles are affected, swallowing is disrupted, and the gait changes. Treatment includes anticholinesterase preparations, vitamins (especially B-group), general restorative treatment, and sometimes the removal of the thymus gland.


Lobzin, V. S. Miasteniia. Leningrad, 1960.
Shefer, D. G. Gipotalamicheskie (dientsefal’nye) sindromy, 2nd ed. Moscow, 1971.
References in periodicals archive ?
Myasthenia gravis is a chronic, autoimmune, neuromuscular disease characterized by weakness and fatigue of voluntary muscles.
Chemical-shift and diffusion-weighted magnetic resonance imaging of thymus in myasthenia gravis: usefulness of quantitative assessment.
A non-muscle-relaxant technique for video-assisted thoracoscopic thymectomy in myasthenia gravis.
Interferon alfa 2 a induced myasthenia gravis was first reported in 1995 in a patient treated for leukaemia.
Subclinical myasthenia gravis causing increased sensitivity to botulinum toxin therapy.
They noted that autologous hematopoietic stem cell transplantation can be considered for select patients at experienced institutions with severe myasthenia gravis for whom the risks of this procedure are outweighed by its potential benefits.
The report reviews pipeline therapeutics for Myasthenia Gravis by companies and universities/research institutes based on information derived from company and industry-specific sources
Total 55 OMG developed generalized myasthenia gravis (GMG) in the follow-up, 47 of 84 patients in the abnormal SFEMG group while 8 of 18 in the normal SFEMG group.
The report reviews key players involved in the therapeutics development for Myasthenia Gravis and enlists all their major and minor projects
Incidence of acetylcholine receptor positive myasthenia gravis in South Africa.
Patients with myasthenia gravis exhibit more sensitivity to non-deporalizing muscle relaxants, so it is better to avoid them during surgical procedure.