Myasthenia


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Related to Myasthenia: Ocular myasthenia

myasthenia

[‚mī·əs·thēn·ē·ə]
(medicine)
Muscular weakness.

Myasthenia

 

(asthenic bulbar paralysis, asthenic ophthalmoplegia, pseudobulbar paralysis, Erb-Goldflam disease), a neuromuscular disease characterized by the pathological, rapid fatigability of striated muscles.

The onset of myasthenia usually occurs between the ages of 20 and 40 years; women are more frequently affected, Autoimmune processes play a part in the development of the disease; antibodies have been discovered in muscle tissue and in the thymus gland. The muscles of the eyelids are often affected and there is ptosis, which varies in degree during the day; the masticatory muscles are affected, swallowing is disrupted, and the gait changes. Treatment includes anticholinesterase preparations, vitamins (especially B-group), general restorative treatment, and sometimes the removal of the thymus gland.

REFERENCES

Lobzin, V. S. Miasteniia. Leningrad, 1960.
Shefer, D. G. Gipotalamicheskie (dientsefal’nye) sindromy, 2nd ed. Moscow, 1971.
References in periodicals archive ?
Myasthenia gravis is a chronic, autoimmune, neuromuscular disease characterized by weakness and fatigue of voluntary muscles.
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A non-muscle-relaxant technique for video-assisted thoracoscopic thymectomy in myasthenia gravis.
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The report reviews pipeline therapeutics for Myasthenia Gravis by companies and universities/research institutes based on information derived from company and industry-specific sources
Total 55 OMG developed generalized myasthenia gravis (GMG) in the follow-up, 47 of 84 patients in the abnormal SFEMG group while 8 of 18 in the normal SFEMG group.
The report reviews key players involved in the therapeutics development for Myasthenia Gravis and enlists all their major and minor projects
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Patients with myasthenia gravis exhibit more sensitivity to non-deporalizing muscle relaxants, so it is better to avoid them during surgical procedure.