The challenges associated with diagnosing these infections are well recognized; sensitivity of histopathology and cytology is low, and cross-reactions between the endemic mycoses
are a particular concern with serologic testing (2-4).
enter the skin and cutaneous tissue usually in a traumatized area (such as a wound); they usually remain localized, but can spread through the lymphatic vessels to other sites.
Econazole and miconazole have also been used intravenously, but absorbed levels are usually too low for treatment of systemic mycoses
The authors of the study published in Mycoses
had no financial conflicts to disclose.
De Pauw B, Walsh TJ, Donnelly JP, Stevens DA, Edwards JE, Calandra T, Pappas PG, Maertens, Lortholary 0, Kauffman CA, Denning DW, Patterson IF, Maschmeyer G, Bille J, Dismukes WE, Herbrecht R, Hope WW, Kibbler CC, Kull-berg BJ, Marr KA, Munoz P, Odds FC, Perfect JR, Restrepo A, Ruhnke M, Segal BH, Sobel JD, Sorrell TC, Viscoli C, Wingard JR, Zaoutis T, Bennett JE; Fungal Infections Cooperative Group; National Institute of Allergy and Infectious Diseases Mycoses
Study Group (EORTC/MSG) Consensus Group: Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive.
Dimorphic systemic mycoses
generally have regional environmental preferences.
A final section details the etiology, epidemiology, pathogenesis, immunology, clinical manifestations, treatment, and prevention of human mycoses
that are AIDS-defining in other regions of the world, e.
1993) and fungi involved in respiratory tract mycoses
(Singh et al.
The diagnosis of deep mycoses
by morphologic methods.
The invention is useful in the diagnosis and treatment for diseases including mycoses
Global Markets Direct's, 'Mycoses
- Pipeline Review, H2 2012', provides an overview of the Mycoses