Mydriatics


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Related to Mydriatics: glaucoma, Tropicamide

Mydriatics

 

substances that cause dilation of the pupil, or mydriasis, by increasing the tension of the radial fibers of the iris (sympathomimetics) or by decreasing the tension of the pupillar sphincter (M-cholinolytic substances, such as atropine, which also cause paralysis of accommodation). Mydriasis may also be caused by synthetic mydriatics.

Mydriatics are used as therapeutic agents (causing functional rest in acute inflammatory diseases and traumas of the eye) and for diagnostic purposes (for example, during examination of the fundus oculi). Mydriatics are applied in the form of solutions or ointments to the conjunctival sac of the eye. The use of mydriatics to treat glaucoma is contraindicated, since mydriatics increase intraocular pressure.

References in periodicals archive ?
7) If used at an excessive dose, NMBAs used in birds as mydriatic agents can have systemic adverse effects, represented by eyelid, neck, and hindlimb muscle paralysis, and possible death.
In 1 study in kestrels (Falco tinnunculus), the mydriatic effect of topical administration of 3 different NMBAs (alcuronium chloride, pancuronium bromide, and vecuronium bromide) was evaluated.
The objectives of this study were to evaluate the efficacy of topically applied rocuronium bromide as a mydriatic agent in kestrels, to verify the possibility of inducing bilateral concurrent mydriasis in these birds, to assess possible local or general adverse effects due to the use of the drug, and to compare the results from this study with those obtained from a study on the use of 3 different NMBAs in the same species of bird of prey.
289 Table 5: Mydriatics & cycloplegics Generic name Rxs (thousands) % Atropine Sulphate 53.
The drugs that can be used by AS optometrists are linked to an approved formulary and include some topical antibiotics, lubricants, mast-cell stabilisers, anti-histamines, one non-steroidal anti-inflammatory as well as miotics and mydriatics (see www.