myelin

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myelin

, myeline
a white tissue forming an insulating sheath (myelin sheath) around certain nerve fibres. Damage to the myelin sheath causes neurological disease, as in multiple sclerosis

myelin

[′mī·ə·lən]
(neuroscience)
A soft, white fatty substance that forms a sheath around certain nerve fibers.
References in periodicals archive ?
2006) Major myelin protein gene (P0) mutation causes a novel form of axonal degeneration.
The team selected seven peptides of myelin proteins to which T cells have shown high reactivity in MS.
Two families present mutations in the myelin protein zero gene (MPZ).
This was measured using Opexa's proprietary Epitope Analysis Assay (EAA) which assessed reactivity across all three key myelin proteins at several time points throughout the 52-week study.
Myelin basic protein, a dominant myelin protein, is selectively synthesized in these sites, for unlike other myelin proteins, MBP enters myelin within minutes of its synthesis.
It's possible that each person with MS has T-cells that recognize different myelin proteins.
Patient-specific MRTCs are expanded in culture with specific peptides identified by assaying peripheral blood mononuclear cell reactivity against peptides derived from the three myelin proteins.
The EAA measures proliferative responses of patient peripheral T-cells upon exposure to peptides of myelin proteins.
The reduction in autoantibodies targeting multiple myelin proteins indicates that BHT-3009 may produce a broad response in a heterogeneous population of MS patients.
We are delighted with the demonstration of tolerization of the immune system to myelin proteins in individuals with multiple sclerosis.
Steinman and his team have designed customized "cocktails" of the DNA that instruct a number of the relevant myelin proteins involved in such B cell responses to the disease.