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(computer science)
Removal or deletion usually of insignificant digits in a number, especially zero suppression.
Optional function in either on-line or off-line printing devices that permits them to ignore certain characters or groups of characters which may be transmitted through them.
Elimination of any component of an emission, as a particular frequency or group of frequencies in an audio-frequency of a radio-frequency signal.



in genetics, a phenomenon that prevents the appearance of a character resulting from mutation and that causes partial or complete restoration of the normal phenotype.

Intragenic suppression is caused by a second (suppressor) mutation in the same gene in which the first (direct) mutation occurred. Intergenic suppression is caused by a second mutation in other genes that are located at a considerable distance from the suppressed gene. In intragenic suppression, a protein coded by a given gene can reacquire functional activity, although its original structure, in contrast to true reverse mutation, or reversion, is not restored. In intergenic suppression, the normal phenotype may be restored in some cases owing to mutations that permit other means of metabolism which do not require the functioning of the given gene. In other cases, the normal phenotype may be restored as a result of mutations that alter the process by which the genetic information of the mutant gene is realized.

The phenomenon of suppression, first discovered in 1920 by the American geneticist A. H. Sturtevant, is used to study the genetic code and other aspects of molecular genetics.


Stent, G. Molekuliarnaia genetika. Moscow, 1974. Chapter 6. (Translated from English.)


References in periodicals archive ?
The report reviews key players involved in the therapeutics development for Chemotherapy Induced Myelosuppression and enlists all their major and minor projects
Although myelosuppression is most important risk in patients given azathioprine, it can be monitored easily with the help of routine blood counts.
It is clear that patients with absent TPMT activity or who are homozygous for TPMT mutations are at increased risk for myelosuppression.
This dosage has been earlier shown to produce severe myelosuppression in mice (Praveenkumar et al.
Many of the side effects of postoperative adjunctive chemotherapy for breast cancer are well established: myelosuppression, hair loss, nausea and vomiting, fatigue, and early menopause.
Some reactions, such as myelosuppression and cerebral hemorrhage, have been fatal.
Myelosuppression was reported in patients with normal baseline laboratory values as well as in patients with pre-existing laboratory abnormalities.
BM stem cells are radiosensitive and predisposed to apoptosis damage in RT, resulting in myelosuppression.
In an oral presentation, the Company will report preclinical data demonstrating the activity of IMGN632 in multiple acute myeloid leukemia (AML) models and patient samples at concentrations far below levels that affect normal bone marrow cells, suggesting the potential for efficacy in AML patients in the absence of or with limited myelosuppression.
ClickPress, Sun May 03 2015] Global Markets Direct's, 'Chemotherapy Induced Myelosuppression - Pipeline Review, H1 2015', provides an overview of the Chemotherapy Induced Myelosuppression's therapeutic pipeline.