Ischemia

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Related to Myocardial ischemia: myocardial infarction

ischemia

[i′skē·mē·ə]
(medicine)
Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.

Ischemia

 

a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.

N. R. PALEEV

References in periodicals archive ?
Devise corrective measures for pipeline projects by understanding Myocardial Ischemia pipeline depth and focus of Indication therapeutics
Acute myocardial ischemia resulted in injury of the cardiomy-ocytes directly, and the persistent ischemia accompanied with the development of heart failure and arrhythmia (Takano et al.
Effects of quercetin on gene and protein expression of NOX and NOS after myocardial ischemia and reperfusion in rabbit.
Severe transmural myocardial ischemia after dipyridamole administration implicating coronary steal.
We categorized patients according to evidence of reversible myocardial ischemia and/or previous MI and calculated LV ejection fraction (LVEF) with the Quantitative Gated Spect software.
Trials containing low--or intermediate-risk patients found a 28% increased risk of all-cause mortality (number needed to harm: 164), and a 116% increased risk of nonfatal stroke (number needed to harm: 275), with a 28% decreased risk of nonfatal MI (number needed to treat: 80), a 59% decreased risk of myocardial ischemia (number needed to treat: 23), and no reduction in rates of cardiovascular mortality or heart failure.
The warning regarding myocardial ischemia will not be added to the pioglitazone label.
The primary endpoint is the improvement in time to onset of electrocardiogram changes diagnostic of myocardial ischemia during exercise treadmill testing at six months.
Rutledge and his associates prospectively studied the risk factors of smoking, hypertension, diabetes, dyslipidemia, inactivity, obesity, depression, and social isolation in a cohort of 734 women with clinical symptoms of myocardial ischemia.
The study, designated as the 'PRECISE' trial, will enroll patients suffering from chronic myocardial ischemia, a severe form of end-stage coronary artery disease, which is estimated to affect hundreds of thousands of patients in Europe and the United States.
Hypertension and PH, due to possible mitral stenosis/insufficiency in association with acute myocardial ischemia, were probably the determinant factors causing this acute episode.

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