Ischemia

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Related to Myocardial ischemia: myocardial infarction

ischemia

[i′skē·mē·ə]
(medicine)
Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.

Ischemia

 

a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.

N. R. PALEEV

References in periodicals archive ?
Patients with diabetes, older adults, and those with prior heart attack or prior bypass surgery are particularly susceptible to silent myocardial ischemia
This second potential indication for CardiAMP investigational cell therapy of chronic myocardial ischemia and refractory angina follows the company's FDA-approved Phase III clinical trial of CardiAMP in ischemic heart failure, which is currently enrolling patients.
This main treatment abolished the coronary vasospasm-related myocardial ischemia and its complication as demonstrated by the same stress testing.
17] and GPBB [10]--have been analyzed for the clinical diagnosis of myocardial ischemia within the first 1-3 h after the onset of chest pain.
The report provides a snapshot of the global therapeutic landscape of Myocardial Ischemia
Results: The study revealed that frequency of positive ETT for silent myocardial ischemia in uncomplicated asymptomatic type 2 diabetic patients was 35.
Fowler III, "Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury," Circulation Research, vol.
Acute myocardial ischemia induced by isoproterenol or ligating the coronary artery
The risk of these adverse events was significantly greater in patients with stable coronary artery disease (CAD) who had angina than in those with neither angina nor silent myocardial ischemia, and higher still in those with both angina and silent ischemia.
Protective roles of quercetin in acute myocardial ischemia and reperfusion injury in rats.
The Akershus Cardiac Examination (ACE) 1 study is a prospective study that includes 200 patients with suspected reversible myocardial ischemia referred to Akershus University Hospital, a teaching hospital in Norway, for myocardial perfusion imaging (MPI) in 2007-2008.
Although CSS is a relatively infrequent cause of symptoms of myocardial ischemia, prompt detection of patients with possible CSS can lead to definitive diagnosis and treatment with vascular surgery, percutaneous angioplasty, or intravascular stent placement.

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