MSTN

(redirected from Myostatin)
Also found in: Dictionary, Medical, Acronyms, Wikipedia.

MSTN

(Monochrome STN) See passive matrix.
References in periodicals archive ?
In the present study, we compared protein turnover among different types of muscle fibers in the presence of myostatin.
Further studies are needed to understand the role of exercise and drug interventions, such as growth hormone regulators, myostatin antagonists, and androgen modulation, on alcohol-related muscle wasting.
The gene therapy was also designed to inhibit action of the myostatin gene, which stops muscle cells from growing.
Myostatin (MSTN; also known as GDF-8) is a member of the TGF-[beta] superfamily, and functions as a negative regulator of skeletal muscle growth in mammals (Lee, 2004; Kollias and McDermott, 2008).
Their objective was to damage, or knock out, both copies of the myostatin gene so that the beagles' bodies would not produce any of the muscle-inhibiting protein that the gene manufactures.
A gripping, fictional story based in Milwaukee, WI, “Strong” explores one man's lifelong struggle with Myostatin Deficiency - a rare muscle disease responsible for extraordinary strength, appearance and stamina.
9) Increased oestrogen stimulation causes several autocrine responses including the up-regulation of platelet-derived growth factor and the down-regulation of activin and myostatin levels which have a significant role in regulating myometrium cellular differentiation.
2+]/calmodulin-dependent kinase (CaMK) signaling, histone deacetylase(HDAC)/ myocyte enhancer factor 2 (MEF2) signaling, myogenic regulatory factor (MRFS) pathway, Ras/MAPK signaling, Myostatin and Wnt signaling, and PGC-l[alpha]/[beta], AMPK and PPAR5 signaling have been shown to regulate gene expression and the choice of MyHC isoforms in the skeletal muscle (Carlsen et al.
report that testosterone supplementation reverses sarcopenia in aging via regulation of myostatin and "multiple signal transduction pathways in sarcopenia," concluding; 'Testosterone reverses sarcopenia through stimulation of cellular metabolism and survival pathway together with inhibition of death pathway.
ABSTRACT:The purpose of this study involves the analysis of mutations in the coding region that was potentially alter myostatin gene expression.
Next the molecular pathways of bone genesis and repair are covered, including myostatin signaling, c-Jun regulation, Lnk, CXCR4, and transcriptional control.
Ryan A, Ivey F, Prior S, Li G, Hafer-Macko C (2011) Skeletal muscle hypertrophy and muscle myostatin reduction after resistive training in stroke survivors.