Myotonia


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Related to Myotonia: myotonia congenita, myotonic dystrophy, myotonia dystrophica

myotonia

[‚mī·ə′tō·nē·ə]
(medicine)
Tonic muscular spasm occurring after injury or infection.

Myotonia

 

a hereditary neuromuscular disease in which a contracted muscle is unable to relax for a long time; muscular relaxation proceeds very slowly. Depending on the clinical course of the disease, congenital, atrophic, cold, and paradoxical forms of myotonia are distinguished. The disease may occur in several members of a family; males are more often affected. There are no marked morphological changes in the nervous system or the muscles. There may be dysfunctions of the autonomic nervous system and the endocrine glands. Increased sensitivity to acetylcholine and potassium are characteristic of the disease. The principal sign of myotonia is impaired myofibril contractility, that is, relaxation of contracted muscles is greatly impaired. The muscles are firm to the touch. Myotonia progresses slowly, with general deterioration frequently setting in after overexposure to low temperatures, mental stress, and excessive fatigue. Treatment includes hormone therapy, vitamin therapy, and physical therapy.

REFERENCE

Badalian, L. O., V. A. Tabolin, and Iu. V. Vel’tishchev. Nasledstvennye bolezni u detei. Moscow, 1971.
References in periodicals archive ?
Whereas myotonia, swallowing dysfunction (Fig 2), cardiac abnormalities, and cataracts minimally impacted participants' lives, fatigue was described as "a vicious enemy" (Maijorie) that exacerbated other symptoms.
Acquired myotonia, weakness and vacuolar myopathy secondary to cyclosporine.
Propranolol, a blocker of [beta]-adrenergic receptors, also exhibits various muscular side effects, including myopathy, (8) weakness, (7) myotonia, (11) muscle cramps, (9) neuromuscular depression, (12) myofibrillar disruption, (10) or elevated CK levels.
Neostigmine has been implicated in worsening neuromuscular block in patients with myotonic dystrophy (2) and in worsening myotonia (2,3).
The Manchester art student said the incident - ending his fivemile Stagecoach ride into the city and leaving him bruised and grazed - was the worst since he was diagnosed in 2006 with muscle problem myotonia congenita, which causes him to fall over.
367 Rancho La Costa, CA 92009 (800) 230-0441 (619) 436-2185 1,2,3,4,5,9 MYOSITIS OSSIFICANS See: Fibrodysplasis Ossificans Progressiva MYOTONIA, CONGENITA See: Muscular Dystrophy MYOTUBULAR MYOPATHY, X-LINKED See also: Muscular Dystrophy Myotubular Myopathy Resource Group 2602 Quaker Dr.
The most common form of muscular dystrophy, DM affects somewhere between 1:3,000 and 1:8,000 people worldwide, and can cause muscle weakness, atrophy and myotonia, as well as problems in the heart, brain, GI tract, endocrine, skeletal and respiratory systems.
The main finding on formal assessment was myotonia in both hands and feet, which was precipitated by cooling.
The Manchester art student said the incident - that left him him bruised and grazed - was the worst since he was diagnosed in 2006 with muscle problem myotonia congenita, which causes him to fall over.
anteriorly Perforation Palatoglossal arch Soft palate Otolaryngology Not required Not required intervention Sequelae Not stated Swallowing difficulties Author Hsu (10) Malik (9) Patient 29-year-old male 72-year-old male Co-morbidities Previous Myotonia congenita.
The most prevalent symptoms include progressive muscular weakness and myotonia, cardiac arrhythmias, cognitive defects, cataracts, as well as well as endocrine, sexual, gastrointestinal and reproductive disturbances.
Mild MD: Patients usually display minor symptoms such as cataract and mild myotonia (sustained contraction).