glycosylation

(redirected from N-linked glycosylation)
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glycosylation

[glī‚käs·ə′lā·shən]
(biochemistry)
A chemical reaction in which glycosyl groups are added to a protein to produce a glycoprotein.
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N-linked glycosylation in the hemagglutinin of influenza A viruses.
Effect of N-linked glycosylation on biological activity.
Likewise, companies with originator molecules can use the new supplement as a method to control or change N-linked glycosylation.
This result is consistent with N-linked glycosylation (Figure 3, panel B).
The consensus sequence for N-linked glycosylation is Asn-X-Ser or Asn-X-Thr, where X can be any amino acid but Pro (31).
These fragments include: K1-4, K1-3, K1-3 without N-linked glycosylation, K1-3 without the interkringle disulfide bond, K2-3, K2-3 without the interkringle disulfide bond, K2-3 without N-linked glycosylation, K4-5, K1, K4, K5, and K2 of tPA.
The technology genetically ligates an external amino acid domain to a therapeutic protein or peptide candidate that results in additional N-linked glycosylation sites on the therapeutic.
alpha]5[beta]1 and [alpha]3[beta]1, possessing a total of 26 potential N-linked glycosylation sites (62).