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naltrexone
(redirected from Naltrexone hydrochloride)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
naltrexone [nal′trek‚zōn]
(pharmacology)
C20H23NO4An opiate receptor antagonist that blocks the effects of endogenous opioids in the brain; used to treat alcoholism.
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It was demonstrated in single dose studies for ELI-216 that no quantifiable blood levels of naltrexone hydrochloride were released at a limit of quantification ("LOQ") of 7.
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The study also helped determine the appropriate levels of naltrexone hydrochloride required to reduce or eliminate the euphoria experienced by subjects who might take crushed product to achieve a "high".
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ELI-216 is a controlled-release oxycodone hydrochloride agonist combined with an opioid antagonist, naltrexone hydrochloride, formulated to deter abuse of the drug.
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