ibuprofen

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ibuprofen

(ī`byo͞oprō'fən), nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxennaproxen
and naproxen sodium,
potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever.
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 and ketoprofenketoprofen
, nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and fever-reducing effects, used to relieve the symptoms of headaches, arthritis, and painful menstruation.
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, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967. Like other NSAIDs, it acts by inhibiting the body's production of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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. Available over the counter in a variety of preparations (e.g., Advil, Motrin, Nuprin), it is commonly used to treat rheumatoid arthritis, gout, and painful menstruation. Side effects include rash, alteration of platelet function and bleeding, and intestinal upset, which can lead to gastritis. Like other NSAIDS, it appears to have no potential for abuse or physical dependence. It should not be used by those who are allergic to aspirin.
References in periodicals archive ?
The same price increase might have occurred if NeoProfen and Indocin had been sold to two separate venture capital funds without any concerns over future reputational consequences or if the parent companies had simply spun off the relevant units in order to maximize their profitability.
In the fall of 2005 Abbott believed that NeoProfen would be approved for sale in 2006, with a stronger label (indicating better safety) than Indocin IV.
There was no dispute that in January 2006 Lundbeck both acquired the rights to NeoProfen and substantially increased the price on the now Lundbeck-labeled Indocin IV.
Neoprofen is used in premature infants with patent ductus arteriosus (PDA), a condition in which a blood vessel in the heart fails to close after birth.
50) Moreover, during the entire short period of their "competition," NeoProfen and Indocin IV were both owned by the same monopolist.
58) There also was the fact that in projecting the initial price for Indocin, before it was even aware that NeoProfen was in development, Lundbeck took into consideration the much higher cost of surgical treatment for PDA, and then lowered the projected price when it learned of NeoProfen.
The FTC challenged Lundbeck's acquisition of the rights to NeoProfen and lost.
This is what the courts in Lundbeck recognized when they held that NeoProfen and Indocin were not in the same market because the choice of drugs depended not on price but on physicians' evaluation of the risk of side effects and general comfort with the drug.
The NeoProfen recall, NDC 67386-122-52, includes product lots 1734991 (expiration date:April, 2011) and 1922319 (expiration date: March, 2012).
Lundbeck A/S (CPH: LUN), said last week it has voluntarily recalled two lots of NeoProfen (ibuprofen lysine) Injection that failed to meet a visible particulate quality requirement.
The development and introduction of NeoProfen demonstrates OVATION's commitment to provide medically necessary therapies for patients suffering from severe illnesses," according to Jeffrey S.