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neurofilament |
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neurofilament [‚nu̇·rō′fil·ə·mənt] (physiology) A type of intermediate filament, composed of three polypeptides (NF-L, NF-M, and NF-H), that helps support and strengthen the axons of nerve cells. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Morphological and biochemical changes of neurofilaments in aged rat sciatic nerve axons. Associated with this neuronal loss is the presence of large eosinophilic inclusions, called Lewy bodies, within the remaining pigmented neurons, made up of a series of proteins, including neurofilaments, [alpha]-synuclein fibrils, ubiquitin, parkin, and proteasomal elements. 6) Immunostaining for neurofilaments and synaptophysin demonstrates the strong positivity of nerve fibers, whereas the perineural epithelial sheaths do not stain. |
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