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neuropathy
(redirected from Neuropathic pain)

   Also found in: Medical, Wikipedia, Hutchinson 0.06 sec.

neuropathy

Disorder of the peripheral nervous system. It may be genetic or acquired, progress quickly or slowly, involve motor, sensory, and/or autonomic (see autonomic nervous system) nerves, and affect only certain nerves or all of them. It can cause pain or loss of sensation, weakness, paralysis, loss of reflexes, muscle atrophy, or, in autonomic neuropathies, disturbances of blood pressure, heart rate, or bladder and bowel control; impotence; and inability to focus the eyes. Some types damage the neuron itself, others the myelin sheath that insulates it. Examples include carpal tunnel syndrome, amyotrophic lateral sclerosis, poliomyelitis, and shingles. Causes include diseases (e.g., diabetes mellitus, leprosy, syphilis), injury, toxins, and vitamin deficiency (e.g., beriberi). See also neuralgia; neuritis.



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XP13512 is a new chemical entity that is a Transported Prodrug of gabapentin, an agent indicated for the treatment of seizure and neuropathic pain.
The ability to heal chronic wounds, reduce neuropathic pain, improve proprioception and balance, and decrease the risk of falling help to improve quality indicators.
The author makes distinctions between various types of pain, including distinctions between somatic pain transmitted by healthy nervous tissue and neuropathic pain that originates in abnormal (eg, demyelinated) nervous tissue.
 
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