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Nitrofurans

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Nitrofurans 

derivatives of furan in which a hydrogen atom is replaced by a nitro group. Nitrofurans have a broad spectrum of antimicrobial action, which is based on their capacity to inhibit respiration of the microbial cell. In surgery, nitrofurans are used for treatment of wounds and for prophylaxis of postoperative complications (Nitrofurazone); in obstetrics, gynecology, and urology they are used for treatment of infectious diseases (Furadonine and Furazolidone). They are also used for treatment of giardiasis and trichomoniasis (Furazolidone).



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One of the most recent instances included Belgium authorities issuing a rapid alert in February detailing the presence of nitrofurans and furazolidone in Indian shrimp products.
Because they are harvested in low-density ponds, antibiotics like Chloramphenicol or Nitrofurans are not necessary to counter the ills of overcrowding.
Resistance to nitrofurantoin was lower than expected, given the documented illicit use of nitrofurans in Portugal by poultry producers in 2002-2003 (DGV, 2004).
 
 
 
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