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nuclear hormone receptor

   Also found in: Wikipedia 0.03 sec.
nuclear hormone receptor [¦nü·klē·ər ′hȯr‚mōn ri‚sep·tər]
(cell and molecular biology)
Any of a superfamily of proteins that directly regulate transcription in response to hormones and other ligands.


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A group of researchers from North America and Europe working in pharmacokinetics, biotechnology, pharmaceutical sciences, biochemistry, and gene expression, as well as gastroenterology and hepatology, provide a review of the historical discoveries and current development of nuclear hormone receptors as transcriptional regulators and the implications of this regulation in drug metabolism, development, clinical drug use, therapeutic potentials, and pharmacogenetics.
The nuclear hormone receptor superfamily includes receptors for thyroid and steroid hormones, retinoids and vitamin D, as well as receptors for unknown ligands.
Moreover, work by other researchers has already shown that several nuclear hormone receptors play crucial roles in the development and functioning of Purkinje cells.
 
 
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