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nuclease |
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nuclease [′nü·klē‚ās] (biochemistry) An enzyme that catalyzes the splitting of nucleic acids to nucleotides, nucleosides, or the components of the latter. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The agent's characteristics include the absence of disease-specific nucleic acids; resistance to radiation, nucleases, and standard sterilization and disinfection methods: and inactivation by protein-modifying procedures. Sangamo is also developing sequence-specific ZFP Nucleases (ZFN(TM)) for therapeutic gene modification as a treatment for a variety of monogenic diseases, such as sickle cell anemia, and for infectious diseases, such as HIV. Nearly all strains secrete hemolysins, nucleases, proteases, lipases, hyaluronidase, and collagenase, which convert host tissues into nutrients required for bacterial growth (3). |
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