ibuprofen

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ibuprofen

(ī`byo͞oprō'fən), nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxennaproxen
and naproxen sodium,
potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever.
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 and ketoprofenketoprofen
, nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and fever-reducing effects, used to relieve the symptoms of headaches, arthritis, and painful menstruation.
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, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967. Like other NSAIDs, it acts by inhibiting the body's production of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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. Available over the counter in a variety of preparations (e.g., Advil, Motrin, Nuprin), it is commonly used to treat rheumatoid arthritis, gout, and painful menstruation. Side effects include rash, alteration of platelet function and bleeding, and intestinal upset, which can lead to gastritis. Like other NSAIDS, it appears to have no potential for abuse or physical dependence. It should not be used by those who are allergic to aspirin.
References in periodicals archive ?
This press release contains forward-looking statements (statements which are not historical facts) within the meaning of the Private Securities Litigation Reform Act of 1995, including statements concerning the Company's rights to the Nuprin trademark, the possibility of near-term sales of ibuprofen products, and the Company's business strategy with respect to its extended release ibuprofen products.
A similar, third-trimester pregnancy warning is required for over-the-counter products that contain ibuprofen (Advil, Motrin, Amersol, Nuprin, Rufen).
Ibuprofen in general (Advil, Motrin and Nuprin combined) accounted for 39% of the responses.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) and is sold over-the-counter under such brand names as: Children's Motrin, Motrin, Advil, Genpril, Haltran, Medipren, Midol 200, Nuprin and PediaProfen.
The studies, which focused on CEFORM(TM) ibuprofen microspheres and involved human volunteers, demonstrated significantly faster onset of absorption than the reference product NUPRIN.