Leukoplakia

(redirected from Oral leukoplakia)
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leukoplakia

[‚lü·kō′plā·kē·ə]
(medicine)
Formation of thickened white patches on mucous membranes, particularly of the mouth and vulva.

Leukoplakia

 

milky-white spots (radius, to 0.5 cm) on the mucous membranes near the skin (for example, on the lower lip) and on the cheeks, tongue, bottom of the mouth, esophagus, cervix uteri, vagina, and urinary bladder.

Leukoplakia is one of the precancerous diseases. Smoking, advanced tooth decay, excessive consumption of alcohol or spices, certain inflammations of the oral cavity, avitaminosis A or B complex, and poorly fitting metal dental bridges, fillings, and crowns may give rise to leukoplakia. The disease occurs in two forms. In simple leukoplakia, the mucous membrane is smooth; its surface resembles mosaic or parquetry. This may be complicated by fissures or erosions. In verrucose leukoplakia, the mucosa is raised and the color varies from pearly to chalky. Patients complain of sensations of petrifaction, burning, and tenderness. Treatment is by surgical removal, electrocoagulation, or radiation therapy.

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References in periodicals archive ?
But even with treatment, oral leukoplakia may recur and is a condition that needs to be monitored regularly.
Paan may contain smokeless tobacco that can cause discoloration of teeth, oral submucous fibrosis and/or oral leukoplakias.
Salivary A malondialdehyde levels in patients with oral leukoplakia.
Its industrial application, however, had been greatly reduced as sanguinarine was reported to be associated with oral leukoplakia (Mascarenhas et al.
Influence of cigarette filters on the risk of developing oral leukoplakia in a Kenyan population.
Smokeless tobacco can cause oral leukoplakia (Fig 8) .
In mouth cancer, it was found that between 7-15% of people who develop oral cancer have white patches known as oral leukoplakia in the tissue lining the mouth.
INGN 234 is a mouthwash formulation of Introgen's p53 tumor suppressor therapy and is being evaluated for the prevention of oral cancers and the treatment of oral leukoplakia.
R]] PDT to prevent AKs and squamous cell carcinomas in immunosuppressed solid organ transplant recipients and is supporting research related to oral leukoplakia in collaboration with the National Institutes of Health (NIH).
Photodynamic therapy (PDT) using topically applied delta-aminolevulinic acid (ALA) for the treatment of oral leukoplakia.
DUSA is researching the use of broad area Levulan[R]PDT to treat AKs and prevent squamous cell carcinomas in immunosuppressed solid organ transplant recipients and is supporting research related to oral leukoplakia in collaboration with the National Institutes of Health (NIH).
An earlier double-blind peer-reviewed human study conducted in India and published in "Nutrition and Cancer," found that consumption of one gram of Spirulina daily for one year resulted in a 45% remission of oral leukoplakia in tobacco chewers compared to a 7% response in the placebo group.