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Osteoclast
(redirected from Osteoclasts)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
osteoclast [′äs·tē·ə‚klast]
(histology)
A large multinuclear cell associated with bone resorption.
(medicine)
A large surgical apparatus through which leverage can be exerted to effect osteoclasis.

Osteoclast 

a cell that is involved in the destruction and resorption of bone tissue in vertebrate animals and man. An osteoclast contains from three to several dozen nuclei and a great many lysosomes, whose hydrolytic enzymes upon release from the osteoclasts resorb the mineral matrix of bone and calcified cartilage.



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It turns out that osteoclasts have receptors on their surface which are activated by a substance called RANK ligand.
Bone is a living tissue that constantly repairs itself - a process regulated by cells called osteoblasts which form new bone and osteoclasts which remove old bone.
Among the cells they produced were osteoclasts, large white cells involved in the brittle bone disease osteoporosis, and eosinophils, which play a role in allergy and asthma.
 
 
 
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