PS1

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PS1

PS1

(1) Sony's PlayStation 1. See PS one.

(2) (PS/1) An early IBM PC. See IBM PS/1.
References in periodicals archive ?
The second, that is hop-1, homolog of PSEN1 [144], in fact shares more homology to human PSEN2; and the third, spe-4, has no clear human counterpart [144].
Therefore, in the PSEN1 iPS cell model, the researchers reconstituted an essential feature in the molecular development of familial Alzheimer's disease.
The microdomain association of PSEN1 and PSEN2 complexes will be achieved by analysis of colocalization with microdomain-specific proteins and lipid probes.
Ringman reported that 159 were at risk for PSEN1 mutations, 19 for PSEN2 mutations, and 34 for APP mutations.
Probable AD with an increased level of certainty is indicated by the core criteria of probable AD plus either evidence of cognitive decline on repeated evaluation or evidence of a genetic mutation in APE PSEN1, or PSEN2 genes.
Prevention efforts for Alzheimer's focus on a mutation that affects the gene PSEN1, which is involved in the production amyloid protein.
A team of scientists from Cardiff University have been examining three genes - APP, PSEN1 and PSEN2 - which are known to cause rare early onset forms of Alzheimer's.
The genetic component is most conspicuous in a relatively small percentage (< 1%) of families that carry disease-causing germline mutations in 1 of 3 genes--APP [amyloid beta (A4) precursor protein], PSEN1 (presenilin 1), or PSEN2 (presenilin 2)--that will invariably lead to AD, often at a relatively young age.
Genetic testing for mutations in the APP, PSEN1, and PSEN 2 genes currently is commercially available (Bird, 2003).