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Pancreatic Juice

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pancreatic juice (păn'krēăt`ĭk, păng'–), secretions of the exocrine portion of the pancreas pancreas , glandular organ that secretes digestive enzymes and hormones. In humans, the pancreas is a yellowish organ about 7 in. (17.8 cm) long and 1.5 in. (3.8 cm) wide.
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 into the small intestine. The juice contains a number of important digestive enzymes enzyme, biological catalyst. The term enzyme comes from zymosis, the Greek word for fermentation, a process accomplished by yeast cells and long known to the brewing industry, which occupied the attention of many 19th-century chemists.
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, including trypsin trypsin, enzyme that acts to degrade protein; it is often referred to as a proteolytic enzyme, or proteinase. Trypsin is one of the three principal digestive proteinases, the other two being pepsin and chymotrypsin.
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, chymotrypsin chymotrypsin , proteolytic, or protein-digesting, enzyme active in the mammalian intestinal tract. It catalyzes the hydrolysis of proteins, degrading them into smaller molecules called peptides. Peptides are further split into free amino acids.
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, carboxypeptidase, lipase lipase , any enzyme capable of degrading lipid molecules. The bulk of dietary lipids are a class called triacylglycerols and are attacked by lipases to yield simple fatty acids and glycerol, molecules which can permeate the membranes of the stomach and small
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, and amylase amylase , enzyme having physiological, commercial, and historical significance, also called diastase. It is found in both plants and animals. Amylase was purified (1835) from malt by Anselme Payen and Jean Persoz.
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. Pancreatic juice is alkaline in nature because of a high concentration of bicarbonate ions; this helps to neutralize the acidic gastric juice gastric juice, thin, strongly acidic (pH varying from 1 to 3), almost colorless liquid secreted by the glands in the lining of the stomach. Its essential constituents are the digestive enzymes pepsin and rennin (see rennet), hydrochloric acid, and mucus.
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 from the stomach. Secretion of pancreatic juice is stimulated by hormones of the duodenum, such as secretin and cholecystokinin, and by nervous impulses through the vagus nerve.
pancreatic juice [¦pan·krē¦ad·ik ′jüs]
(physiology)
The thick, transparent, colorless secretion of the pancreas.

Pancreatic Juice 

a complex digestive juice secreted by the acinar cells of the pancreas and discharged into the duodenum.

The pancreatic juice is a clear, colorless liquid, alkaline in reaction (pH 8.3–8.6). Its specific gravity is 1.007–1.009. Among the enzymes it contains are trypsin, chymotrypsin, and carboxypeptidase, enzymes which split up proteins; lipase, which splits fats; and amylase and lactase, which break down carbohydrates. Pancreatic juice also contains proteins (mainly globulins), creatinine, urea, uric acid, and some trace elements. The average amount discharged in a healthy person in 24 hours is 1.5–2 liters. The secretion and discharge of the pancreatic juice is regulated by humoral and neural means. Other regulatory agents are secretin—a hormone produced by the acid stomach contents in the mucosa of the small intestine—and the secretory fibers of the vagus and sympathetic nerves. Physiological stimulators of pancreatic-juice flow are hydrochloric and some other acids, bile, and food.



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We know that people who have a family history of inflammation of the pancreas tend to have a higher risk, so doctors are testing their pancreatic juice for pre-cancerous cell changes.
Lipase, found in stomach and pancreatic juices also enters the body via the food we eat; digests fats, helping to maintain correct gall bladder function.
Lipase, found in stomach and pancreatic juices also enters the body via the food we eat; digests fats, helping to maintain correct gall bladder function.
 
 
 
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