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A growth pattern of epithelial tumors in which the proliferating epithelial cells grow outward from a surface, accompanied by vascularized cores of connective tissue, to form a branching structure.



a benign tumor of man and animals; its basic structural element is a connective-tissue papilla covered with epithelium and containing vessels. The growth of the papillae in various directions sometimes gives a papilloma the appearance of a cauliflower. The presence of numerous papillomas is called papillomatosis. Papillomas are most commonly found on the skin, although they sometimes occur on mucous membranes. In man, they may be congenital or may result from chronic inflammatory irritation. Some papillomas are viral in origin, for example, those of the sexual organs. The recommended therapy is surgical removal.

Papillomatosis in animals is caused by locally specific viruses. It affects cattle, horses, dogs, and rabbits and occasionally goats, sheep, and wild animals. The infection is caused by diseased animals; natural infection results from contact between diseased and healthy animals. The disease is long in duration. Isolated coral-like papillomas appear and then spread. Their surface is dry, horny, and cracked. When injured, papillomas bleed and become infected and ulcerous. Diagnosis is based on clinical and histological examination. Treatment generally consists of surgical removal.


References in periodicals archive ?
The tests were performed on papiloma virus treated with the Scotia Pharmaceuticals drug, Foscan, and a compact laser source developed by Spectra Science, which uses low-cost plastic materials to replace a costly dye laser.
En septiembre de 2008, el Departamento de Salud del Reino Unido inicio un programa de inmunizacion contra el virus del papiloma humano (VPH) para ninas de 12-13 anos de edad, para la prevencion del cancer cervical, que es causado con mayor frecuencia por dos tipos de VPH.
Existen remedios en la forma de nuevas modalidades de prevencion y tratamiento, como vacunas contra el virus del papiloma humano (VPH), pruebas rapidas de VPH, inspeccion visual del cervix con acido acetico (IVAA) y crioterapia.
Los avances tecnologicos en el diagnostico de ITS, desarrollo de microbicidas y la deteccion sistematica y vacunacion del viras del papiloma humano deben estar a la disposicion de los paises en desarrollo y las personas mas necesitadas mundialmente.
En cuanto a la actividad anticancerigena del ALC, se ha demostrado reduccion del numero de papilomas en un modelo de carcinogenesis epidermica en raton (6).