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agonist |
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agonist [′ag·ə‚nist] (biochemistry) A chemical substance that can combine with a cell receptor and cause a reaction or create an active site. (physiology) A contracting muscle that is resisted or counteracted by another muscle, called an antagonist, with which it is paired. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Phase 2, currently underway, is designed to demonstrate the capability of both standardized protocols against a set of test compounds comprising weak estrogen partial agonists and a known negative. The RPE distinguishes between full agonists (RPE = 100) and partial agonists (RPE [is less than of equal to] 50) (31) and is formally analogous to the RIE in the yeast assay. Negro-Vilar, entitled "Third Generation SERMs: Partial Agonists with Full Benefits," will update Ligand's research advances to develop further improved molecules that retain all the benefits of second-generation SERMs (i. |
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